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The rare case that does not settle, or that comes with real pain, is the one worth a clinician's eyes

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10.1016/j.bbrc.2015.08.092 145 WangA.LiT.AnP.YanW.ZhengH.WangB.et al (2017)

The reason for excluding all patients with heart failure was due to our inability to determine the presence of congestive heart failure stage IV, which is contraindicated for GLP1 RA use
Overgaard RV, Petri KC, Jacobsen LV, Jensen CB
