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If you want a deeper explanation of the hormone pathway behind these medications, our guide on what GLP-1 is is a helpful place to start

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Although some people may find it helpful, there is a lack of evidence supporting the efficacy of black cohosh for reduction of hot flushes 12 , and the NICE guidelines state Do not offer [] black cohosh to treat menopausal symptoms in women with breast cancer. Lab research has shown that black cohosh can inhibit the two core enzymes that convert tamoxifen to endoxifen, meaning it may reduce the function of tamoxifen