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This effect helps explain why nausea, vomiting, bloating, constipation, and other digestive symptoms can occur, especially during dose escalation or at higher doses

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Stained sections were examined under an optical microscope

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It is also worth considering that fatigue attributed to GLP-1 therapy may actually reflect underlying conditions such as hypothyroidism, anemia, sleep apnea, or depression, which should be evaluated if tiredness persists