what is a glp-1 drug made from Understanding GLP Drugs: They Are and Why People Take Them Compound versions of GLP-1 drugs

doi: 10.1016/j.diabres.2012.10.017

Hunt JE, Holst JJ, Jeppesen PB, et al

J Inflammation Res

Dulaglutide is covalently linked to human immunoglobulin IgG 4 heavy chain molecules to reduce immunogenicity, enhance water solubility, and avoid degradation by DPP-4

As of February 2024, 15 GLP-1 medications had received FDA approval for blood sugar and weight control, with more in development

Because the analysis was retrospective, it could not establish whether the use of GLP-1 receptor agonists had directly improved survival or reduced recurrence, nor could it determine whether any apparent benefit resulted from weight loss, improved cardiovascular health, better glucose control, anti-inflammatory effects or other biological mechanisms