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Namely, gastrointestinal distress

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For patients on tirzepatide, which produces a more pronounced caloric deficit due to its dual GIP/GLP-1 mechanism, methylated B12 provides upgraded energy and cognitive support during the weight loss phase

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During episodes of illness with severe vomiting or diarrhoea, maintain hydration if possible and contact your healthcare team promptly if unable to keep fluids down, as there is a risk of dehydration and acute kidney injury

Return to the operating room, evaluated in six RCTs with a total sample size of 587 pooled patients