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A team of researchers from the University of Iowa has unveiled concerns about the use of semaglutide, a widely prescribed GLP-1 receptor agonist for type 2 diabetes and obesity, in patients with neuroendocrine neoplasms (NENs)
-1Glucagon like peptide-1, GLP-1LGLP-1R
My clinical takeaway: Dont discontinue GLP-1s reflexively for fear of NAION
The OASIS 1 and 2 trials compared the therapeutic efficacy and clinical safety profile of once-daily oral semaglutide 50 mg versus placebo on overweight and obese participants without T2DM and both with and withoutT2DM, respectively
