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AlphaFold predictions of complexes between NS3h, RNA and/or NS5B suggest that NS3h both remodels the cis-acting RNA elements and unwinds the terminal stem-loop of the HCV genome rendering the template accessible for de novo initiation of () strand synthesis by NS5B

Bioluminescence imaging For in vitro luciferase assays, cells were plated in 12-well plates, allowed to attach overnight and then treated with BSO (100 M), cisplatin (1 M) and/or TMZ (10 M)

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Popular diet trends for inflammatory bowel diseases: claims and evidence

10.1021/acs.molpharmaceut.0c00474 48 FebbraroF.AndersenK
