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Fisman, E

Although predominantly found in the gastrointestinal and neural tracts, GLP-1R is also present in other tissues, including kidney, skeletal and smooth muscle, liver and adipose [39]

The Florida Weight-Loss Consumer Bill of Rights posted on TeleHealth Med's site notes that rapid weight loss of more than 1.5 to 2 pounds per week may cause serious health problems

doi: 10.1056/NEJMoa2401943 204 SkovJDejgaardAFrkirJHolstJJJonassenTRittigSet al

These medications slow gastric emptying and reduce appetite, which can inadvertently decrease fluid intake while increasing the risk of dehydration through gastrointestinal symptoms like nausea, vomiting, and diarrhea

found no difference in meal-stimulated GLP-2 plasma or tissue concentrations between IBD and non-IBD individuals