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This provides enough time for dose titration and a stable period for data collection

Introduction Mood disorders, including major depressive disorder (MDD) and bipolar disorder (BD), remain a major cause of disability worldwide, with lifetime prevalence exceeding 15% for depression and up to 3% for bipolar disorder, with more than 400 million people affected by depression [1]

Upper arm injections appear only twice per cycle and are optional for self-injectors

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Additionally, Tesofensine also affects the reward pathways in the brain, making it less rewarding to eat food, leading to further decrease in food intake