sitagliptin glp 1 agonist GLP-1: Actions on Beta-cell Mass and Function Mechanism of action of GLP-1

Weve heard a lot about glucagon-like peptide 1 (GLP-1) receptor agonists lately, primarily via the brand names Ozempic and Wegovy

Both are GLP-1 receptor agonists that help reduce appetite and improve blood sugar control.Add image Are weight loss injections like Wegovy and Mounjaro available on the NHS

But what we are pretty much sure of now, which has been clarified over the past two decades or so, is there's a very very strong biological basis for developing obesity

Every employer survey we reviewed flagged GLP-1s as a top driver of rising health spend for 2026

Wegovy FDA-approved specifically for chronic weight management

The Phase 2 trial published in the New England Journal of Medicine in 2023 provides the clearest picture of its effects