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Such acute caloric restriction has been shown to rapidly reverse -cell dysfunction and restore insulin secretion in those with a shorter duration of T2D [25,31,34] , with hepatic insulin sensitivity and fasting plasma glucoses normalizing as early as 1 week even in the absence of significant weight loss [34]
Muller TD, Sullivan LM, Habegger K, Yi CX, Kabra D, Grant E et al
eClinicalMedicine, 68, 102429
doi: 10.1007/s12035-017-0622-3 203 BombaMGranzottoACastelliVMassettiNSilvestriECanzonieroLMTet al
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