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Table of Contents Understanding the GLP-1 Mechanism Ozempic and Mounjaro: What Sets Them Apart Integrating GLP-1 Agonists into Clinical Practice Addressing Patient Expectations and Concerns Understanding the GLP-1 Mechanism GLP-1 receptor agonists mimic the natural incretin hormone, stimulating insulin secretion while inhibiting glucagon release in a glucose-dependent manner

Obes Surg 34(2):303309 Vinciguerra F et al (2023) High-dose liraglutide improves metabolic syndrome in poor responders to bariatric surgery

10.1016/j.dsx.2022.102427

8 Thus, it fosters reduction in appetite, food quantity and calorie intake
Central glucagon-like peptide 1 receptor-induced anorexia requires glucose metabolism-mediated suppression of AMPK and is impaired by central fructose