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Leptin signaling in the nucleus tractus solitarii increases sympathetic nerve activity to the kidney
(This trial investigates the cardiovascular outcomes of oral semaglutide in patients with type 2 diabetes, examining potential adverse effects like dehydration.) Lindamood CA, Taylor JR, Martel J, et al
J Clin Endocrinol Metab 88 : 57475752 Broglio F et al
It also acts on appetite-regulating centers in the hypothalamus, reducing hunger signals and food cravings
