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This narrative review discusses the justification for focus on lean mass preservation and reviews the status of relevant drugs in development.

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In an animal study, the ingredient SNAC, which helps semaglutide survive the stomach and enter the bloodstream, was associated with changes in gut bacteria, inflammation markers, and a brain linked protein

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This was prompted by the publication of a landmark article in the New England Journal of Medicine addressing the impact of this medication in a large clinical trial