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4 As if that isn't challenging enough, shifting estrogen levels can also lead to insulin resistance, which can elevate your blood sugar levels and trigger weight gain
The STEP 5 trial showed ongoing weight loss through 104 weeks of treatment, with participants maintaining a 15.2% body weight reduction at the two-year mark

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Conclusions: The 4-week treatment with semaglutide and tirzepatide had a neutral effect on bone mass compared with the controls, and most of the bone microarchitecture parameters were also comparable between groups in diabetic mice

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