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Attention has focused on inhibition of SGLT4 (in intestine and kidney) and particularly SGLT5 (in kidney) to reduce intake and increase elimination of fructose [89]
135,136,137 SIRT3 also enhances cellular antioxidant capacity through augmenting the reducing power, NADPH, and increasing the activity of antioxidant enzymes, such as SOD2 and catalase
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