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To view or add a comment, sign in What are pharmacokineticsand why do they matter for harm reduction

At 48 weeks, mean percentage changes in body weight from baseline were approximately: In the 12 mg arm, roughly 100% of participants achieved at least 5% body-weight loss, about 83% reached 15% loss, around 63% achieved 20% loss, and approximately 26% crossed the 25% threshold

Mazdutide's Phase 3 safety database is substantially larger, showing mostly mild to moderate GI events with no new safety signals when compared head-to-head with semaglutide in DREAMS-3

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