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Cardiovascular Effects Dose-dependent increases in heart rate were observed with retatrutide: Heart rate increases peaked at approximately 24 weeks Gradually declined thereafter while remaining elevated above baseline This pattern is similar to that observed with other GLP-1 receptor agonists[4] The clinical significance of these heart rate changes requires further evaluation in larger and longer-term studies
Discover what UK clinical evidence reveals about musculoskeletal symptoms with semaglutide, potential causes, management strategies, and when to seek medical advice for muscle discomfort during treatment.
NYT's opinion page: science can't keep pace with how people are actually using these drugs
Wegovy (semaglutide) can be prescribed for adults with a BMI 30 kg/m or BMI 27 kg/m with at least one weight-related comorbidity
