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doi: 10.1016/j.afres.2025.101127

GLP-1 medications slow gastric emptying by design, that's part of how they reduce appetite and improve postprandial glucose control

Delays in digestion may end up contributing to an additional problem of the gastrointestinal tract: obstruction

These advanced medications are FDA-approved for obesity, helping patients achieve and sustain meaningful change when lifestyle changes alone fall short
Analysts predict the obesity drug market could reach around $100 billion by 2030
Key mechanisms include: Appetite suppression Liraglutide acts on receptors in the brain's appetite centres, particularly the hypothalamus, reducing hunger and increasing feelings of fullness [11] [12] Delayed gastric emptying The medication slows the rate at which food leaves the stomach, prolonging satiety after meals Improved glycaemic control Liraglutide enhances insulin secretion in response to elevated blood glucose and suppresses inappropriate glucagon release Saxenda is administered as a once-daily subcutaneous injection, with doses gradually increased over five weeks from 0.6 mg to the maintenance dose of 3.0 mg daily
