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Most commonly, patients will present with a variety of generalized symptoms including, but not limited to, nausea/vomiting, dehydration, hypoglycemia, diarrhea and abdominal pain

Improper blood vessels are prone to leak, bleed, and scar, leading to vision loss and other retinal complications

Early theoretical concerns emerged from animal studies and isolated reports, prompting extensive investigation by researchers and UK regulators

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Clinical Takeaways As the prevalence of obesity, insulin resistance, metabolic syndrome and associated health complications continue to rise, targeting GLP-1 activity has emerged as a promising strategy in improving cardiometabolic health and encouraging sustainable weight loss

Safety profiles in adults 1875 years old show similar tolerability, with gastrointestinal side effects declining after 48 weeks of therapy