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Maintaining regular meals matters even when appetite drops, since skipping food may cause blood sugar dips that bring on headaches

Tiredness, swelling/redness/itching at the injection site, loss of appetite, vomiting, nausea, upset stomach, constipation, and diarrhea are possible side effects of Zepbound

Metformin belongs to a drug class called biguanides

Limitations and strengths This study is based on comprehensive longitudinal data from multiple nationwide registries in Denmark, where information can be linked across registries due to the unique personal identification number

Wei H, Bu R, Yang Q, Jia J, Li T, Wang Q, Chen Y

Several trials report meaningful fertility gains after moderate to large weight reductions, including one study that found an average 10.3% bodyweight loss associated with improved reproductive markers