mayo clinic tirzepatide Menopause Hormone Therapy May Boost GLP-1 Drug Benefits Sex, not age, predicts #tirzepatide

Thus, reductions in energy intake with GLP-1Rbased pharmacotherapies reflect not only diminished appetite but may also involve a concomitant shift in food preference toward less energy-dense foods

GLP-1 medications offer several benefits such as reducing high blood pressure, enhancing lipid profile management, treating fatty liver disease, lowering the risk of heart and kidney diseases, and slowing the advancement of diabetes-related kidney damage

Precautions: Avoid if you have a history of medullary thyroid carcinoma (MTC) or MEN 2

(4) Wootten D, et al

Methods We analyzed cases involving a GLP-1RA reported to the National Poison Data System during 20172022

User-reported experiences with extended Wegovy dosing 10-11 day spacing: Some users report manageable results with minimal hunger return 14-day (biweekly) spacing: Most report significant hunger return and reduced effectiveness Appetite control: Generally good for the first 7-8 days, diminishing noticeably afterwards Side effects: More variable and less predictable than with weekly dosing Weight loss: Typically slower than with weekly dosing Overall sentiment: Financially appealing, but less effective Safe alternatives to consider instead of extended dosing Rather than adapting medication schedules without clinical guidance, consider these evidence-based alternatives: 1