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When Concurrent Use Requires Extra Caution or Alternative Approaches Patients with existing gastrointestinal disorders (gastroparesis, inflammatory bowel disease, severe reflux), those on high semaglutide doses, or those with chronic opioid dependency should discuss alternative pain management strategies with their providers

Management of cardiovascular diseases in patients with obesity
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Mendes D, Alves C, Batel-Marques F

The cardiovascular benefits of semaglutide are attributed to direct cardiac effects (protection against myocardial ischemia, reduction of epicardial adipose tissue, and improved cardiac contractility) and vascular effects (vasodilation and enhanced endothelial function) [32]

Trends in diagnostics, surgical treatment, and prognostic factors for outcomes in medullary thyroid carcinoma in Norway: a nationwide population-based study

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