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While tirzepatide improves cardiometabolic risk markers, dedicated cardiovascular outcome data are awaited

Participants : Over 1,600 adults with obesity or overweight and type 2 diabetes

The adverse effects were not reported, and no dropouts were registered

Metformin also reduces the risk of certain cancers (such as breast cancer) linked to high blood sugar levels

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A rat model of visceral pain sensitivity also showed a decrease in circulating amounts of bioactive GLP-1 (23)
