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There was a mean decrease in heart rate of 0.3 bpm in placebo-treated patients

GLP-1 supplements are not reviewed or approved by the FDA and theres no evidence that they work

In April 2025, according to an article published by the Heart Rhythm Society, a recent clinical study, TRANSFORM-AF, found that GLP-1 receptor agonists (GLP-1 RAs), typically used for diabetes, may reduce atrial fibrillation (AF)-related events in patients with both obesity and AF

Phase 2 trials investigated once-weekly subcutaneous doses ranging from 1 mg to 12 mg, administered via a gradual escalation schedule
Growth hormone secretagogues specifically require quality sleep to deliver their full benefit

This compares to a bioavailability of 89% for subcutaneous injections in humans 18