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10.1038/nm.3009 42 FlorianH.WangD.ArnoldS
The interplay of glucagon-like peptide-1 receptor trafficking and signalling in pancreatic cells
Therefore, it was further inferred that exendin-4 might first bind to GLP-1R and act on the PKA pathway, which in turn affects the Wnt/-catenin pathway in the osteoblasts, reduces the expression of sclerostin, and promotes the formation of bone (Kim et al., 2013)
Steady-state liraglutide concentrations are known to be reached after 35 days of treatment
If you have any of the following contact your doctor or GLP-1 provider
J Arthroplasty 39(3):716720
