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Indeed, the dysregulated production and combined activity of different MMPs and TIMPs, in association to chronical inflammation, can hinder normal ECM turnover and architecture restoration, leading to fibrotic epilogue [84, 123,124,125]

The findings, published Monday in the Annals of Internal Medicine, may seem counterintuitive, said co-author Dr

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The results of preclinical, genetic, and experimental clinical studies indicate that short- or long-acting GLP-1RAs independently attenuate the acute side effects of addictive drugs or reduce the chronic effects of drug abuse [82]
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