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GLP-1s affect "brain areas that control hunger but also [act] on taste bud cells and brain regions that process taste and reward," study coauthor and a professor at the University of Bayreuth, Othmar Moser, said in a press release

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Success will require collaborative efforts to develop and validate predictive biomarkers, establish optimal treatment sequencing algorithms, evaluate long-term safety of novel agents and combinations, and demonstrate meaningful impact on patient-centered outcomes including hospitalization, surgery, disability, and quality of life

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