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When there is a severe insult to the liver, the liver cells can die, and we can see this in a blood test when we look at the inflammation in the liver. In severe cases, people can die from liver failure or they need a liver transplant to save their life. That patient is unlikely to need a transplant

Each purification cycle adds cost, time, and risk of batch failure

Canadian Geriatrics Journal 25(3):254-261

Conversely, failure to obtain coverage can lead to unaffordable out-of-pocket costs (as high as ~$14,000 annually per patient ( [1] ))

Half the patients began taking GLP-1 drugs while the other half took DPP-4 inhibitors, another class of Type 2 diabetes medications

273279, journals.lww.com/co-endocrinology/fulltext/2023/12000/glucagon_like_peptide_1_receptor_agonists_and.2.aspx, Purwar, Ananya, and Shailesh Nagpure