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All participants (body mass index greater than 25 kg/m2) had uncontrolled diabetes and were treated with metformin as monotherapy

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Most patients experience modest hunger increase during weeks 3-6 of the wean, which typically plateaus rather than continuing to spike

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Nevertheless, further studies are needed to determine the safety, tolerability, and clinical effectiveness of GLPs analogs in therapy

Anagliptin, a DPP-4 inhibitor, suppresses proliferation of vascular smooth muscles and monocyte inflammatory reaction and attenuates atherosclerosis in male apo E-deficient mice