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Description
Based on current evidence, there is no established association between semaglutide and increased risk of ischemic colitis in the major cardiovascular outcome...
the most commonly reported AEs were gastrointestinal-related and were more frequent with semaglutide (all doses) than with placebo
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However, more studies are needed.
Oral administration of peptide therapeutics faces challenges because of the distinct environment of the gastrointestinal tract
