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Therapeutic doses of tirzepatide are 5mg to 15mg

However, there are major differences between these medications, including how they affect your body and how long you should use them

These drugs also improve gonadotropins (LH and FSH), which play a key role in hormone regulation

By decreasing gastric emptying, they also reduce post-meal glucose spikes, which is attractive for diabetes and weight management treatment. These drugs work differently from traditional weight loss medications: They modulate appetite and hunger suppression rather than stimulating the nervous system to increase calorie burn

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Moreover, they show that metformin enhances the expression of the genes encoding the receptors for both GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) in mouse islets and also increases the effects of GIP and GLP-1 on insulin secretion from beta cells