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The overall economics will also depend on the required dose and frequency of administration
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Exenatide exerts a PKA-dependent positive inotropic effect in human atrial myocardium: GLP-1R mediated effects in human myocardium
A large historical cohort study of 543,595 patients demonstrated that GLP-1RA treatment over 7 years did not increase the incidence of pancreatic cancer, confirming its safety profile in this malignancy (179)
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