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Because each category reaches weight loss through a different pathway, no single mechanism explains how every peptide in this guide works

Understanding how metabolic and genetic factors may relate to disease progression can support more informed conversations with healthcare providers about treatment options

Pharmacy: Once approved, the prescription is sent to your local pharmacy

doi: 10.1530/JOE-14-0445

And with data showing that around half of patients stop using them within a year, many people may be in for a shock the next time they step on the scale

Since arriving on the market in 2005 for the treatment of Type 2 diabetes, Circana said, the class of drugs known as glucagon-like peptide-1 receptor agonists (GLP-1s) have upended diabetes treatment and revolutionized how doctors and consumers approach weight management. These medications are designed to mimic the effects of a naturally occurring hormone that helps regulate blood sugar and slows digestion, which promotes the feeling of satiety, Circana added, noting that the first GLP-1 medication was approved for weight loss in 2014