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Where Phase 2 Left Off The Phase 2 trial of Retatrutide published in The New England Journal of Medicine (Jastreboff et al., 2023) was a 48-week, randomised, double-blind, placebo-controlled dose-ranging study in adults with obesity (BMI 2750) without type 2 diabetes
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Pharmaceutical companies then synthesized longer-acting versions, including semaglutide, which required only once-weekly dosing instead of daily injections
Author Contributions Conceptualization, J.D.M.-M., S.B.-C., S.A.O.-B., L.C.T.-A., S.F.-C., L.C.-V., L.C.R.-R., C.A.C.-O
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C., & Erlanson-Albertsson, C
