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Further, haemodialysis did not affect the pharmacokinetics of oral semaglutide.45 Based on the two above trials, hepatic impairment and renal impairment should not affect dose recommendations for oral semaglutide, which is similar to semaglutide administered subcutaneously

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Obes (Silver Spring) 20:330342 Colhoun HM, Lingvay I, Brown PM et al (2024) Long-term kidney outcomes of semaglutide in obesity and cardiovascular disease in the SELECT trial

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