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The difference between the two medications was smaller in real-world practice (5 percentage points) than in the SURMOUNT-5 trial (6.5 percentage points), which may suggest that behavioural support helps to enhance weight-loss outcomes on GLP-1 medications

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A smaller number find they can maintain at sub-milligram doses when combined with consistent exercise and dietary habits

Gentle swirling rather than shaking dissolves the compound without damaging peptide bonds

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Adequate hydration is crucial, particularly with diarrhea, vomiting, or constipation
