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Results Eight thousand nine hundred ninety-one of the 17,598 participants randomized to pantoprazole/placebo (51%) had eGFR recorded at baseline and open-label extension enrollment and were included in the rate of eGFR change population (mean age 67 [SD 8] years, 22% female, mean baseline eGFR 75 [SD 17.5] ml/min per 1.73 m 2 )

They then compared rates of osteoporosis (bones that become weak and prone to fracture), gout (an inflammatory arthritis caused by excess uric acid crystals in the joints), and osteomalacia (softening of bone tissue) between the two groups

These conditions, such as type 2 diabetes, heart disease, and some cancers, can incur significant healthcare costs throughout your life

While they dont treat the autoimmune condition directly, lowering inflammation may ease common symptoms like fatigue and joint pain

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