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Dosing Strategy and Formulation Choices to Minimize Headache Occurrence Slower titration schedulesstarting at 2.5 mg weekly for 4 weeks before escalationreduce headache incidence compared to standard 5 mg initiation

This dual action produces approximately 5-8% greater weight loss in head-to-head trials

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While the Squadron moved to Bowen, Queensland in May 1942 in response to the increasing frequency of Japanese raids on Port Moresby it continued to conduct reconnaissance, anti-submarine and occasional bombing operations over the waters around New Guinea
