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The proposed mechanisms indicate that BBR holds significant promise as an oral antidiabetic agent

Key Takeaways Effectiveness: Tirzepatide may lead to greater average weight loss in trial populations
Mitochondrial Dysfunction and Mitophagy in Type 2 Diabetes: Pathophysiology and Therapeutic Targets

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In order to validate our results that the pharmaceutical properties of peptide 1 can be improved by substituting amino acids with oligourea triads, we conducted a series of IPGTT studies on the three best hybrids 14 , 22 and 23 with peptide 1 as control (Fig