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[1] Common adverse effects include nausea, vomiting, diarrhoea, and injection site reactions

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The Japan GLP-1 receptor agonistmarket size was valued at USD 1.39 billion in 2025 and is projected to reach USD 1.55 billion in 2026

Jing F, Zou Q, Wang Y, Cai Z, Tang Y (2021) Activation of microglial GLP-1R in the trigeminal nucleus caudalis suppresses central sensitization of chronic migraine after recurrent nitroglycerin stimulation

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