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Description
The primary hypothalamic target for ghrelin are neurons in ARC that express and release NPY and AgRP in the lateral hypothalamus and LHA to mediate orexigenic effect in the brain (16, 17)

Medication not included

doi: 10.1111/1753-0407.70004 14 SunYZhangSBaoTJiangZHuangWXuXet al
Gradual dose increases reduce nausea and diarrhea, which lowers the chance of dehydration

Treatment is typically initiated within specialist weight management services for adults meeting specific BMI and comorbidity criteria, with ongoing monitoring and continuation requirements
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Cost: Insurance coverage varies widely
