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Ghrelin, CCK, GLP-1, and PYY(336): Secretory controls and physiological roles in eating and glycemia in health, obesity, and after RYGB

This dosing flexibility is an important consideration in the Mounjaro vs Trulicity decision

DOI: 10.1016/S2665-9913(26)00074-3 Cite This Page : ScienceDaily

DPP-4 inhibitors (gliptins) Shortly after the demonstration that the enzyme DPP-4 is responsible for the rapid inactivation of GLP-1, the idea of inhibiting DPP-4 to prolong the duration of action of GLP-1 (and glucose-dependent insulinotropic polypeptide [GIP]) was put forward (reviewed in [34])

Cleve Clin J Med