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In addition, activation of GLP-1R regulates mitochondrial over fission by the cAMP/PKA pathway while improving mitochondrial function in A-treated astrocytes and ameliorating pathological lesions in AD (Xie et al., 2021)

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Potential Side Effects of GLP-1 That May Affect IBS Gastrointestinal side effects are the most commonly reported adverse reactions with GLP-1 receptor agonists, occurring in a significant proportion of patients, particularly during treatment initiation and dose escalation

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