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All ICSRs were spontaneous (100.0%) and reported by non-healthcare professionals (57.3%)

That matches semaglutide and given the slope would probably reach nearly 20% weight loss in a 72 week trial by itself , which would only be 2% behind CagriSema

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Thomas Nikolaj Bang Liller, Department of Cardiology, Heart Centre, Copenhagen University Hospital, Copenhagen, Denmark
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N Engl J Med 373(23):22472257 Muskiet MHA, Tonneijck L, Huang Y, Liu M, Saremi A, Heerspink HJL et al (2018) Lixisenatide and renal outcomes in patients with type 2 diabetes and acute coronary syndrome: an exploratory analysis of the ELIXA randomised, placebo-controlled trial