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Pharmacol Res 210:107517 [DOI] [PubMed] [Google Scholar] 8.Lazzaroni E, Ben Nasr M, Loretelli C, Pastore I, Plebani L, Lunati ME et al (2021) Anti-diabetic drugs and weight loss in patients with type 2 diabetes

When estrogen levels are adequate, GLP-1 signals are amplified

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Concerns about pancreatitis first surfaced in adverse event databases and case reports, sparking a contentious discussion

Therefore, reducing fat deposition through GIP receptor antagonism still hold promising therapeutic potential supported by animal models and the fact that individuals with loss-of-function GIPR genetic variants have a lower body mass index (BMI) (39, 9799)
