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n programul SURMOUNT (suprapondere/obezitate), cel mai citat studiu este SURMOUNT-1, de asemenea n NEJM (Jastreboff i colab., 2022)

Sites of protease/peptidase vulnerabilities in GLP-1 were removed by amino acid substitution and the peptide backbone was bis-lipidated to promote MEDI7219 reversible plasma protein binding without affecting potency

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