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High blood sugar over time can affect nerve function and blood flow, leading to reduced sensation, vaginal dryness, and difficulty reaching orgasm

Tirzepatide is available in escalating doses (2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, and 15 mg) to allow gradual titration, minimizing gastrointestinal side effects while optimizing therapeutic response

Here's some insight: United Healthcare: Coverage often includes tirzepatide, subject to prior authorization and documented weight loss efforts

The Wegovy Prescribing Information lists renal adverse events and recommends monitoring in patients with renal impairment, particularly when gastrointestinal symptoms occur

CAS: 2381272-06-4

Direct head-to-head comparison of tirzepatide vs semaglutide was conducted in the SURPASS-2 trial, which showed tirzepatide 15mg weekly produced significantly greater HbA1c reduction (-2.46% vs -1.86%) and weight loss (-12.4 kg vs -6.2 kg) compared to semaglutide 1mg weekly in type 2 diabetes