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Tirzepatide activates both GLP-1 and GIP receptors, enhancing appetite suppression and metabolic improvement through complementary but non-overlapping pathways

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Semaglutide is a long-acting GLP-1 receptor agonist

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La eleccin entre un comprimido diario o una inyeccin semanal para el tratamiento de la obesidad ofrece a los pacientes y profesionales de la salud la oportunidad de seleccionar la opcin que mejor se adapte a sus preferencias individuales de tratamiento.

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[DOI] [PubMed] [Google Scholar] 28.Yildirim Simsir I, Soyaltin UE, Cetinkalp S

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In subjects with T2DM, weekly administration of tirzepatide at doses of 5 mg, 10 mg, or 15 mg was associated with greater weight loss compared to placebo ( 6.3 kg, 8.4 kg, and 9.4 kg, respectively), and 1.7 kg, 4.8 kg, and 7.2 kg greater weight loss compared to selective GLP-1 receptor agonists, demonstrating a dose-dependent effect sustained for up to 2 years [48]

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