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Resultant hepatic glycogen synthesis allows for sufficient glycogen mobilization and hepatic glucose production during the subsequent fasting state

GH reports research grants from the Netherlands Organization for Scientific Research (vidi 016.156.445), CardioVascular Research Initiative, European Union and the Klinkerpad fonds, institutional research support from Aegerion, Amgen, AstraZeneca, Eli Lilly, Genzyme, Ionis, Kowa, Pfizer, Regeneron, Roche, Sanofi, and The Medicines Company

Both agents lower blood glucose through different mechanisms, raising concerns about additive effects and increased hypoglycaemia risk, especially with insulin or sulfonylureas

These interventions are relatively new, and trials are ongoing for new indicators of obesity-related diseases

This can affect appetite, fullness and how quickly the stomach empties